Optibac Probiotics Bifido & Fibre - Vegan Digestive Probiotic Supplement with FOS Fibre to Maintain Regularity & 25 Billion Bacterial Cultures - 30 Sachets

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Sheil B. et al (2006), ‘Consumption of the probiotic Bifidobacterium infantis35624 influences subsequent immune responses to in vitrochallenge of isolated murine Peyer’s patch cells with bacterial stimuli’, Gastroenterology,130(4 Suppl 2):A371. Tomoda T, Nakano Y Kageyama T. Intestinal Candida Overgrowth and Candida Infection in Patients with Leukemia: Effect of Bifidobacterium Administration. Bifidobacteria Microflora 1988;7(2):71-74. Czajeczny D, Kabzińska K, Wójciak RW. Does probiotic supplementation aid weight loss? A randomized, single-blind, placebo-controlled study with Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 supplementation. Eat Weight Disord. 2020. View abstract. Bifidobacterium animalis subsp. lactis (B. lactis) is a type of probiotic ("good" bacteria) that lives in the intestines. It produces lactic and acetic acid. Bifidobacterium lactisstrains: Bifidobacterium lactisBi-07 ® , Bifidobacterium lactisBB-12 ®, Bifidobacterium lactisHN019and Bifidobacterium lactisBl-04 ® .

Symonds E.L. et al (2007), ’Probiotic prevention of digestive enzyme damage in a mouse model of Salmonella’, Gastroenterology,132(4 Suppl 2):A714-5. Kim CS, Cha L, Sim M, et al. Probiotic supplementation improves cognitive function and mood with changes in gut microbiota in community-dwelling older adults: A randomized, double-blind, placebo-controlled, multicenter trial. J Gerontol A Biol Sci Med Sci 2021;76(1):32-40. View abstract. Further relevant studies: Gad et al., (2011), Johnson et al., (2011), Konieczna et al., (2013), Scully et al (2013) Symonds et al., (2012), van der Kleij et al., (2008), O’Mahony et al., (2005), Sheil et al (2007), Shanahan et al (2006), Sommerfield et al (2003), Symonds et al (2007), Wall et al (2010), von Wright et al (2002). Bifidobacterium infantis35624 and Mood Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60. View abstract.

References

Sommerfield D. et al (2005), ‘Effect of probiotic feeding on Salmonellatranslocation in a Mouse model’, Gastroenterology,128:A120. (Abstract 770) Bastürk A, Artan R, Yilmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol 2016;27(5):439-43. View abstract.

There is minimal research on the effects of probiotics on pregnant women and recent mothers. So it’s best they avoid potential complications and pass on the B. Bifidum. The elderly Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial. Biomed Pharmacother 2021;141:111915. View abstract. Segata, N. et al. Metagenomic microbial community profiling using unique clade-specific marker genes. Nature methods 9, 811–814, doi: 10.1038/nmeth.2066 (2012). Multiple research studies indicate that B. bifidum is helpful in the following areas. Symptoms of IBS As some properties & benefits of probiotics may be strain-specific, this database provides even more detailed information at strain level. Read more about the strains that we have included from this genus below.

Leyer GJ, Li S, Mubasher ME, et al. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 2009;124:e172-e179. View abstract. Odamaki, T., Xiao, J. Z., Sakamoto, M., Kondo, S., Yaeshima, T., Iwatsuki, K., Togashi, H., Enomoto, T., and Benno, Y. Distribution of different species of the Bacteroides fragilis group in individuals with Japanese cedar pollinosis. Appl.Environ.Microbiol. 2008;74(21):6814-6817. View abstract. Roberfroid MB. Prebiotics and probiotics: are they functional foods? Am J Clin Nutr. 2000;71(6 Suppl):1682S-7S; discussion 1688S-90S. View abstract.

Samimi M, Dadkhah A, Haddad Kashani H, Tajabadi-Ebrahimi M, Seyed Hosseini E, Asemi Z. The effects of synbiotic supplementation on metabolic status in women with polycystic ovary syndrome: a randomized double-blind clinical trial. Probiotics Antimicrob Proteins. 2019;11(4):1355-1361. View abstract. Butler CC, Lau M, Gillespie D, et al. Effect of probiotic use on antibiotic administration among care home residents: A randomized clinical trial. JAMA. 2020;324(1):47-56. View abstract. Further relevant studies: Bairead et al (2005), Brenner (2009a), Brenner et al (2009b), Chang et al (2005), Charbonneau et al., (2005a), Charbonneau et al., (2005b), Charbonneau et al., (2005c), Charbonneau et al., (2005d), Chen K-S et al (2005), Mayer (2008), O’Mahony et al., (2005), Quigley et al (2005a), Quigley et al (2005b). Bifidobacterium infantis35624 and Inflammatory Conditions - Ulcerative Colitis, Chronic Fatigue Syndrome and PsoriasisVentura, M., Canchaya, C., Fitzgerald, G. F., Gupta, R. S. & van Sinderen, D. Genomics as a means to understand bacterial phylogeny and ecological adaptation: the case of bifidobacteria. Antonie Van Leeuwenhoek 91, 351–372, doi: 10.1007/s10482-006-9122-6 (2007). Iwabuchi N, Hiruta N Kanetada S Yaeshima T Iwatsuki K Yasui H. Effects of Intranasal Administration of Bifidobacterium longum BB536 on Mucosal Immune System in Respiratory Tract and Influenza Virus Infection in Mice. Milk Science 2009;38(3):129-133.

Milani, C. et al. Genomic encyclopedia of type strains of the genus Bifidobacterium. Applied and environmental microbiology 80, 6290–6302, doi: 10.1128/AEM.02308-14 (2014). Soh, S. E., Aw, M., Gerez, I., Chong, Y. S., Rauff, M., Ng, Y. P., Wong, H. B., Pai, N., Lee, B. W., and Shek, L. P. Probiotic supplementation in the first 6 months of life in at risk Asian infants--effects on eczema and atopic sensitization at the age of 1 year. Clin.Exp.Allergy 2009;39(4):571-578. View abstract. Airaksinen K, Yeung N, Lyra A, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes 2019;10(6):617-627. View abstract.

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Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Desbonnet L. et al (2008), ‘The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat’, Journal of Psychiatric Research, 43(2):164-74.