Molecular Biology of the Cell

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Alexander Johnson received his PhD from Harvard University and is a professor of microbiology and immunology at the University of California, San Francisco. Thus, the parent organism hands down information specifying, in extraordinary detail, the characteristics that the offspring will have. As always, we are also indebted to a large number of scientists whose generous help has been essential for making the text as clear, up-to-date, and accurate as possible. The outcome is a single-strand polymer molecule whose sequence of nucleotides faithfully represents a portion of the cell’s genetic information, even though it is written in a slightly different alphabet—consisting of the four RNA monomers instead of the four DNA monomers.

We live in a world that presents humanity with many challenging problems related to cell biology, including declining biodiversity, climate change, food insecurity, environmental degradation, resource depletion, and animal and plant diseases. Costoya (Universidade de Santiago de Compostela, Spain), Michael Cox (University of Wisconsin, Madison), Nancy Craig (Johns Hopkins University), Emily D. The firm soon expanded its program beyond the Institute, publishing books by celebrated academics from America and abroad. It must also express its information, by letting the information guide the synthesis of other molecules in the cell. Acknowledgments xvii United Kingdom), Chris Doe (University of Oregon, Eugene), Russell Doolittle (University of California, San Diego), W.

Thus, whereas the cell’s archive of genetic information in the form of DNA is fixed and sacrosanct, RNA transcripts are mass-produced and disposable. Cells, Genomes, and the Diversity of Life The surface of our planet is populated by living things—organisms—curious, intricately organized chemical factories that take in matter from their surroundings and use these raw materials to generate copies of themselves. In the living cell, however, DNA is not synthesized as a free strand in isolation, but on a template formed by a preexisting DNA strand. At Quizlet, we’re giving you the tools you need to take on any subject without having to carry around solutions manuals or printing out PDFs! Adopting instructors can obtain access to the site from their sales representative, who can be identified by visiting wwnorton .

Each strand then can serve as a template, in the way just described, for the synthesis of a fresh DNA strand complementary to itself—a fresh copy, that is, of the hereditary information (Figure 1–3). But life employs this free energy to drive a very complex system of chemical reactions that create and maintain the intricate organization of its cells, all as specified by the hereditary information in those cells. Part III presents the principles of the main experimental methods for investigating and analyzing cells; here, a section titled “Mathematical Analysis of Cell Function” in Chapter 8 provides an extra dimension in our understanding of cell regulation and function.It describes the current understanding of cell biology and includes basic biochemistry, experimental methods for investigating cells, the properties common to most eukaryotic cells, the expression and transmission of genetic information, the internal organization of cells, and the behaviour of cells in multicellular organisms. Asmus (Centre College), Yu Chen (University of Massachusetts), Elizabeth Good (University of Illinois, Urbana-Champaign), Douglas R.